Katedra molekulární biologie a genetiky
Department of molecular biology and genetics
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  • Identifying the Translatome of Mouse NEBD-Stage Oocytes via SSP-Profiling; A Novel Polysome Fractionation Method

    In the new publication with colleagues at Charles University (Prague), Czech Academy of Sciences (IAPG - Libechov) and the University of Edinburgh (UK), Alexander W. Bruce and Lenka Gahurová report a new method of polysome profiling (applicable to downstream RNA-Seq to detect polysome associated mRNAs undergoing translation) from biologically scarce material (e.g. NEBD mouse oocytes).

  • p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos

    p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos

  • Gabriela Krejcova and Adam Bajgar in eLife

  • A chromosome-level genome assembly of Cydia pomonella provides insights into chemical ecology and insecticide resistance

    Petr Nguyen and Martina Dalíková from the Faculty of Science, University of South Bohemia in České Budějovice and the Biology Center AS CR and their colleagues from a large international scientific team mapped the arrangement of the codling moth Cydia pomonella genome at chromosome level, which includes sex chromosome Z and part of sex chromosome W

  • The general mRNA exporters Mex67 and Mtr2 play distinct roles in nuclear export of tRNAs in Trypanosoma brucei

    The team of Zdenek Paris published an original study in the Nucleic Acid Research, in which they identified new candidates responsible for tRNA transport in Trypanosoma brucei.


About our department

Head of the department: doc. Mgr. Tomáš Doležal, Ph.D.

Department of Molecular Biology and Genetics was established on Aug 1st 2016 by fusion of Department of Molecular Biology and Department of Genetics. Most of the research activity is focused to functional analysis of genes using various model organisms from Trypanosoma, C. elegans, Drosophila and other insects to mice. Graduate students are trained in modern methods of molecular genetics including mutagenesis, RNAinterference, transgenesis and cell culture techniques. The department is closely linked to Biology Centre of the Academy of Sciences of the Czech Republic (Institute of Parasitology and Entomology).The department is responsible for the Experimental Biology Master’s programme and for the Molecular, and Cell Biology, and Genetics Doctoral programme.

 

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