• Age‐related differences in the translational landscape of mammalian oocytes

    New publication in Aging Cell arising from collaborative work of Alexander W. Bruce and Lenka Gahurová with Andrej Susor at the Institute of Animal Physiology & Genetics, Libechov (Czech Academy of Sciences).

  • The genetic architecture of a host shift: An adaptive walk protected an aphid and its endosymbiont from plant chemical defenses

    In their new scientific study, Peter Nguyen from the Faculty of Science and the Biology Center ASCR and his colleagues investigated genetic changes that resulted from a change of the host plant of the green peach aphid (Myzus persicae).

  • Winners of Image Competition 2019

    click to see the winning images

  • Identifying the Translatome of Mouse NEBD-Stage Oocytes via SSP-Profiling; A Novel Polysome Fractionation Method

    In the new publication with colleagues at Charles University (Prague), Czech Academy of Sciences (IAPG - Libechov) and the University of Edinburgh (UK), Alexander W. Bruce and Lenka Gahurová report a new method of polysome profiling (applicable to downstream RNA-Seq to detect polysome associated mRNAs undergoing translation) from biologically scarce material (e.g. NEBD mouse oocytes).

  • p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos

    p38-mitogen activated kinases mediate a developmental regulatory response to amino acid depletion and associated oxidative stress in mouse blastocyst embryos


About our department

Head of the department: doc. Mgr. Tomáš Doležal, Ph.D.

Department of Molecular Biology and Genetics was established on Aug 1st 2016 by fusion of Department of Molecular Biology and Department of Genetics. Most of the research activity is focused to functional analysis of genes using various model organisms from Trypanosoma, C. elegans, Drosophila and other insects to mice. Graduate students are trained in modern methods of molecular genetics including mutagenesis, RNAinterference, transgenesis and cell culture techniques. The department is closely linked to Biology Centre of the Academy of Sciences of the Czech Republic (Institute of Parasitology and Entomology).The department is responsible for the Experimental Biology Master’s programme and for the Molecular, and Cell Biology, and Genetics Doctoral programme.

 

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