Jan Ženka


RNDr. Jan Ženka, CSc.

(born in 1955, Svitavy)
 

phone: +420 387 776 274,  +420 774 550 724

e-mail: jan@zenka.net

building C PřF JU, door 02 038

Dr Ženka graduated from Faculty of Science, Department of Biochemistry, Jan Evengelista Purkyně University, Brno (1979). Postgraduate studies (biology) he finished in 1984. As member of Department of Medical Biology he is focused on study of cancer immunotherapy. Dr Ženka gives lectures on Cancer therapy for Bachelors (KME/066) and Cancer therapy for Masters (KME/074).

 

Selected publications:

 Uher, O.; Caisova, V.; Hansen, P.; Kopecky, J.; Chmelar, J.; Zhuang, Z.; Zenka, J.; Pacak, K. (2019) Coley's immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity. Seminars in Oncology, doi:10.1053/j.seminoncol.2019.10.004

Caisová, V.; Li, L.; Gupta, G.; Jochmanová, I.; Jha, A.; Uher, O.; Huynh,T.T.; Miettinen, M.; Pang, Y.; Abunimer, L.; Niu, G.; Chen, X.; Ghayee, H.K.; Taïeb, D.; Zhuang, Y.; Zenka, J.; Pacak, K. (2019) The significant reduction or  complete eradication of subcutaneous and metastatic lesions in a  pheochromocytoma mouse model after immunotherapy using mannan-BAM, TLR ligands, and-anti-CD40. Cancers, 11, 654; doi:10.3390/cancers11050654.

 Caisova, V.; Uher, O.; Nedbalova, P.; Jochmanova, I.; Kvardova, K.; Masakova, K.; Krejcova, G.; Padoukova, L.; Chmelar, J.; Kopecky, J.; Zenka, J. (2018) Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis. Int Immunopharmacol , 59, 86-96.

Caisova, V.; Vieru, A.; Kumzakova, Z.; Glaserova, S.; Husnikova, H.; Vacova, N.; Krejcova, G.; Padoukova, L.; Jochmanova, I.; Wolf, K. I.; Chmelar, J.; Kopecky, J.; Zenka, J. (2016) Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model. BMC Cancer , 16, 940.

Janotova, T.; Jalovecka, M.; Auerova, M.; Svecova, I.; Bruzlova, P.; Maierova, V.; Kumzakova, Z.; Cunatova, S.; Vlckova, Z.; Caisova, V.; Rozsypalova, P.; Lukacova, K.; Vacova, N.; Wachtlova, M.; Salat, J.; Lieskovska, J.;  Kopecky, J.; Zenka, J. (2014) The use of anchored agonists of phagocytic receptors for cancer immunotherapy: B16-F10 murine melanoma model. PLoS One, 9, e85222.