Publications


List of publications

2019

Barčák D., Yoneva A., Sehadová H., Oros M., Gustinelli A., Kuchta R. (2019): Complex insight on microanatomy of larval “human broad tapeworm” Dibothriocephalus latus (Cestoda: Diphyllobothriidea). Parasit Vectors 12: 408.

Bertolini E., Schubert F.K., Zanini D., Sehadová H., Helfrich-Förster C., Menegazzi P. (2019): Life at high latitudes does not require circadian behavioral rhythmicity under constant darkness. Curr Biol 29: 3928-3936.

Caisová V., Li L., Gupta G., Jochmanová I., Jha A., Uher O., Huynh T.T., Miettinen M., Pang Y., Abunimer L., Niu G., Chen X., Ghayee H.K., Taïeb D., Zhuang Z., Ženka J., Pacák K. (2019): The significant reduction or complete eradication of subcutaneous and metastatic lesions in a pheochromocytoma mouse model after immunotherapy using mannan-BAM, TLR ligands, and anti-CD40. Cancers 11: 654.

Carreras-González A., Barriales D., Palacios A., Montesinos-Robledo M., Navas N., Azkargorta M., Peña-Cearra, Tomás-Cortázar J., Escobes I., Pascual-Itoiz M.A., Hradiská J., Kopecký J., Gil-Carton D., Prados-Rosales R., Abecia L., Atondo E., Martín I., Pellón A., Elortza F., Rodríguez H., Anguita J. (2019): Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions. PLoS Pathog 15: e1008163.

Chmelař J., Kotál J., Kovaříková A., Kotsyfakis M. (2019): The use of tick salivary proteins as novel therapeutics. Front Physiol 76: 2003-2013.

Hönig V., Palus M., Kašpar T., Zemanová M., Majerová K., Hofmannová L., Papežík P., Sikutová S., Rettich F., Hubálek Z., Rudolf I., Votýpka J., Modrý D., Růžek D. (2019): Multiple lineages of Usutu virus (Flaviviridae, Flavivirus) in blackbirds (Turdus merula) and mosquitoes (Culex pipiens, Cx. modestus) in the Czech Republic (2016-2019). Microorganisms 7: 568.

Hönig V., Švec P., Marek L., Mrkvička T.,Zubriková D., Wittmann M., Masař O., Szturcová D., Růžek D., Pfister K., Grubhoffer L. (2019): Model of risk of exposure to Lyme borreliosis and tick-borne encephalitis virus-infected ticks in the border area of the Czech Republic (South Bohemia) and Germany (Lower Bavaria and Upper Palatinate). Int J Environ Res Public Health 16: 10.3390/ijerph16071173.

Kotál J., Stergiou N., Buša M., Chlastáková A., Beránková Z., Řezáčová P., Langhansová H., Schwarz A., Calvo E., Kopecký J., Mareš M., Schmitt E., Chmelař J., Kotsyfakis M. (2019): The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin. Cell Moll Life Sci 76: 2003-2013.

Koubová J., Jehlík T., Kodrík D., Sábová M., Šima P., Sehadová H., Závodská R., Frydrychová Čapková R. (2019): Telomerase activity is upregulated in the fat bodies of prediapause bumblebee queens (Bombus terrestris). Insect Biochem Mol Biol 115: 103241.

Kratochvíl J., Kahoun D., Kylián O., Štěrba J., Kretková T., Kousal J., Hanuš J., Vaclová J., Prysiazhnyi V., Sezemský P., Fojtíková P., Lieskovská J., Langhansová H., Krakovský I., Straňák V. (2019): Nitrogen enriched C:H:N:O thin films for improved antibiotics doping. Appl Surf Sci 494: 301-308.

Krejčová G., Danielová A., Nedbalová P., Kazek M., Strych L., Chawla G., Tennessen J.M., Lieskovská J., Jindra M., Doležal T., Bajgar A. (2019): Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense. Elife 8: e50414.

Řežábková L., Brabec J., Jirků M., Dellerba M., Kuchta R., Modrý D., Parker W., Jirků Pomajbíková K. (2019): Genetic diversity of the potentially therapeutic tapeworm Hymenolepis diminuta (Cestoda: Cyclophyllidea). Parasitol Int 71: 121-125.

Selinger M., Tykalová H., Štěrba J., Věchtová P., Vavrušková Z., Lieskovská J., Kohl A., Schnettler E., Grubhoffer L. (2019): Tick-borne encephalitis virus inhibits rRNA synthesis and host protein production in human cells of neural origin. PLoS Negl Trop Dis 13: e0007745.

Sobotková K., Parker W., Levá J., Růžková J., Lukeš J., Jirků Pomajbíková K. (2019): Helminth therapy – from the parasite perspective. Trends Parasitol 35: 501-515.

Uher O., Caisová V., Hansen P., Kopecký J., Chmelař J., Zhuang Z., Ženka J., Pacák K. (2019): Coley´s immunotherapy revived: Innate immunity as a link in priming cancer cells for an attack by adaptive immunity. Semin Oncol 46: 385-392.

2018

Bezawork-Geleta A., Wen H., Dong L., Yan B., Vider J., Boukalová S., Krobová L., Váňová K., Zobalová R., Sobol M., Hozák P., Novais S.M., Caisová V., Abaffy P., Naraine R., Pang Y., Zaw T., Zhang P., Šindelka R., Kubišta M., Zuryn S., Molloy M.P., Berridge M.V., Pacák K., Rohlena J., Park S., Neužil J. (2018): Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints. Nat Commun 9: 2221.

Caisová V., Uher O., Nedbalová P., Jochmanová I., Kvardová K., Masáková K., Krejčová G., Paďouková L., Chmelař J., Kopecký J., Ženka J. (2018): Effective cancer immunotherapy based on combination of TLR agonists with stimulation of phagocytosis. Int Immunopharmacol 59: 86-96.

Frutos E., Karlík M., Jiménez J.A., Langhansová H., Lieskovská J., Polcar T. (2018): Development of new β/α″-Ti-Nb-Zr biocompatible coating with low Young's modulus and high toughness for medical applications. Mater Des 142: 44-55.

Hartmann D., Šíma R., Konvičková J., Perner J., Kopáček P., Sojka D. (2018): Multiple legumain isoenzymes in ticks. Int J Parasitol 48: 167-178.

Jalovecká M., Hartmann D., Miyamoto Y., Eckmann L., Hajdušek O., O'Donoghue A.J., Sojka D. (2018): Validation of Babesia proteasome as a drug target. Int J Parasitol Drugs Drug Resist 8: 394-402.

Jirků Pomajbíková K., Jirků M., Levá J., Sobotková K., Morien E., Parfrey L.W. (2018): The benign helminth Hymenolepis diminuta ameliorates chemically induced colitis in a rat model system. Parasitology 145: 1324-1335.

Kratochvíl J., Kahoun D., Štěrba J., Langhansová H., Lieskovská J., Fojtíková P., Hanuš J., Kousal J., Kylián O., Straňák V. (2018): Plasma polymerized C:H:N:O thin films for controlled release of antibiotic substances. Plasma Process Polym 15: 1700160.

Kratochvíl J., Štěrba J., Lieskovská J., Langhansová H., Kuzminova A., Khalakhan I., Kylián O., Straňák V. (2018): Antibacterial effect of Cu-C:F nanocomposites deposited on PEEK substrates. Mater Lett 230: 96-99.

Lieskovská J., Páleníková J., Langhansová H., Chmelař J., Kopecký J. (2018): Saliva of Ixodes ricinus enhances TBE virus replication in dendritic cells by modulation of pro-survival Akt pathway. Virology 514: 98-105.

Pang Y., Lu Y., Caisová V., Liu Y., Bullová P., Huynh T.T., Zhou Y., Yu D., Fryšák Z., Hartmann I., Taïeb D., Pacák K., Yang C. (2018): Targeting NAD+/PARP DNA repair pathway as a novel therapeutic approach to SDHB-mutated cluster I pheochromocytoma and paraganglioma. Clin Cancer Res 24: 3423-3432.

Růžková J., Květoňová D., Jirků M., Lhotská Z., Stensvold C.R., Parfrey L.W., Jirků Pomajbíková K. (2018): Evaluating rodent experimental models for studies of Blastocystis ST1. Exp Parasitol 191: 55-61.

Širmarová J., Salát J., Palus M., Hönig V., Langhansová H., Holbrook M.R., Růžek D. (2018): Kyasanur Forest Disease virus infection activates human vascular endothelial cells and monocyte-derived dendritic cells. Emerg Microbes Infect 7: 175.

Xin M., Štěrba J., Shaliutina-Kolesova A., Dzyuba B., Lieskovská J., Boryshpolets S., Siddique M.A.M., Kholodnyy V., Lebeda I., Linhart O. (2018): Protective role of antifreeze proteins on sterlet (Acipenser ruthenus) sperm during cryopreservation. Fish Physiol Biochem 44: 1527-1533.

2017

Cabezas-Cruz A., Mateos-Hernández L., Chmelař J., Villar M., de la Fuente J. (2017): Salivary prostaglandin E2: Role in tick-induced allergy to red meat. Trends Parasitol  33: 495-498.

Elsterová J., Palus M., Širmarová J., Kopecký J., Niller H.H., Růžek D. (2017): Tick-borne encephalitis virus neutralization by high dose intravenous immunoglobulin. Ticks Tick Borne Dis 8: 253-258.

Chmelař J., Kotál J., Langhansová H., Kotsyfakis M. (2017): Protease inhibitors in tick saliva: The role of serpins and cystatins in tick-host-pathogen interaction. Front Cell Infect Microbiol 7: 216.

Palus M., Vancová M., Širmarová J., Elsterová J., Perner J., Růžek D. (2017): Tick-borne encephalitis virus infects human brain microvascular endothelial cells without compromising blood-brain barrier integrity. Virology 507: 110-122.

Rezková M., Kopecký J. (2017): Anti-tumour necrosis factor activity in saliva of various tick species and its appearance during the feeding period. Folia Parasitol 64: 032.

2016

Caisová V., Vieru A., Kumžáková Z., Glaserová S., Husníková H., Vácová N., Krejčová G., Paďouková L., Jochmanová I., Wolf K.I., Chmelař J., Kopecký J., Ženka J. (2016): Innate immunity based cancer immunotherapy: B16-F10 murine melanoma model. BMC Cancer 16: 940.

Černý J., Selinger M., Palus M., Vavrušková Z., Tykalová H., Bell-Sakyi L., Štěrba J., Grubhoffer L., Růžek D. (2016): Expression of a second open reading frame present in the genome of tick-borne encephalitis virus strain Neudoerfl is not detectable in infected cells. Virus Genes 52: 309-316.

Elsterová J., Palus M., Širmarová J., Kopecký J., Niller H.H., Růžek D. (2016): Tick-borne encephalitis virus neutralization by high dose intravenous immunoglobulin. In press.

Ergunay K., Tkachev S., Kozlova I., Růžek D. (2016): A review of methods for detecting tick-borne encephalitis virus infection in tick, animal, and human specimens. Vector Borne Zoonotic Dis 16: 4-12.

Eyer L., Nencka R., Huvarová I., Palus M., Joao Alves M., Gould E.A., De Clercq E., Růžek D. (2016): Nucleoside inhibitors of Zika virus. J Infect Dis 214: 707-711.

Eyer L., Šmídková M., Nencka R., Neča J., Kastl T., Palus M., De Clercq E., Růžek D. (2016): Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus. Antiviral Res 133: 119-129.

Chmelař J., Chatzigeorgiou A., Chung K.J., Prucnal M., Voehringer D., Roers A., Chavakis T. (2016): No role for mast cells in obesity-related metabolic dysregulation. Front Immunol 7: 524.

Chmelař J., Kotál J., Karim S., Kopáček P., Francischetti I.M., Pedra J.H., Kotsyfakis M. (2015): Sialomes and mialomes: A system-biology view of tick tissues and tick-host interactions. Trends Parasitol 32: 242-254.

Chmelař J., Kotál J., Kopecký J., Pedra J.H., Kotsyfakis M. (2016): All for one and one for all on the tick-host battlefield. Trends Parasitol, 32: 368-377.

Valdés J.J., Gil V.A., Butterill P.T., Růžek D. (2016): An all-atom, active site expoloration of antiviral drugs that target Flaviviridae polymerases. J Gen Virol 97: 2552-2565.

Waldmannová E., Caisová V., Fáberová J., Sváčková P., Kovářová M., Sváčková D., Kumžáková Z., Jačková A., Vácová N., Nedbalová P., Horká M., Kopecký J., Ženka J. (2016): The use of Zymosan A and bacteria anchored to tumor cells for effective cancer immunotherapy: B16-F10 murine melanoma model. Int Immunopharmacol 39: 295-306.

Wang X., Shaw D.K., Sakhon O.S., Snyder G.A., Sundberg E.J., Santambrogio L., Sutterwala F.S., Dumler J.S., Shirey K.A., Perkins D.J., Richard K., Chagas A.C., Calvo E., Kopecký J., Kotsyfakis M., Pedra J.H. (2016): The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4-mediated inflammasome activation. Infect Immun 84: 1796-1805.

Zouharová D., Lipenská I., Fojtíková M., Kulich P., Neča J., Slaný M., Kovařčík K., Turánek-Knötigová P., Hubatka F., Celechovská H., Mašek J., Koudelka S., Procházka L., Eyer L., Plocková J., Bartheldyová E., Miller A.D., Růžek D., Raška M., Janeba Z., Turánek J. (2016): Antiviral activities of 2,6-diaminopurine-based acyclic nukleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1). Vet Microbiol 184: 84-93.

2015

Bílý T., Palus M. Eyer L., Elsterová J., Vancová M., Růžek D. (2015): Electron tomography analysis of tick-borne encephalitis virus infection in human neurons. Sci Rep 5: 10745.

Chmelař J., Kotál J., Karim S., Kopáček P., Francischetti I.M., Pedra J.H., Kotsyfakis M. (2015): Sialomes and mialomes: A system-biology view of tick tissues and tick-host interactions. Trends Parasitol, doi: 10.1016/j.pt.2015.10.002. [Epub ahead of print]

Elsterová J., Černý J., Müllerová J., Šíma R., Coulson S.J., Lorentzen E., Strom H., Grubhoffer L. (2015): Search for tick-borne pathogens in the Svalbard Archipelago and Jan Mayen. Polar Res 34: 27466.

Eyer L., Valdés J.J., Gil V.A., Nencka R., Hřebabecký H., Šála M., Salát J., Černý J., Palus M., De Clercq E., Růžek D. (2015): Nucleoside inhibitors of tick-borne encephalitis virus. Antimicrob Agents Chemother 59: 5483-5493.

Formanová P., Černý J., Bolfíková-Černá B., Valdés J.J., Kozlová I., Dzhioev Y., Růžek D. (2015): Full genome sequences and molecular characterization of tick-borne encephalitis virus strains isolated form human patients. Ticks Tick Borne Dis 6: 38-46.

Hönig V., Švec P., Halas P., Vavrušková Z., Tykalová H., Kilian P., Vetišková V., Dorňáková V., Štěrbová J., Šimonová Z., Erhart J., Štěrba J., Golovchenko M., Rudenko N., Grubhoffer L. (2015): Ticks and tick-borne pathogens in South Bohemia (Czech Republic): Spatial variability in Ixodes ricinus abundance, Borrelia burgdorferi and tick-borne encephalitis virus prevalence. Ticks Tick Borne Dis. 6: 559-567.

Klein M., Brühl T.J., Staudt V., Reuter S., Grebe N., Gerlitzki B., Hoffmann M., Bohn T., Ulges A., Stergiou N., de Graaf J., Löwer M., Taube C., Becker M., Hain T., Dietzen S., Stassen M., Huber M., Lohoff M., Chagas A.C., Andersen J., Kotál J., Langhansová H., Kopecký J., Schild H., Kotsyfakis M., Schmitt E., Bopp T. (2015): Tick salivary sialostatin L represses the initiation of immune responses by targeting IRF4-dependent transcription in murine mast cells. J Immunol 195: 621-631. 

Kodrík, D., Stašková T., Jedličková V., Weyda F., Závodská R., Pflegerová J. (2015): Molecular characterization, tissue distribution, and ultrastructural localization of adipokinetic hormones in the CNS of the firebug Pyrrhocoris apterus (Heteropetra, Insecta). Gen Comp Endocr 210: 1-11.

Kotál J., Langhansová H., Lieskovská J., Andersen J.F, Francischetti I.M., Chavakis T., Kopecký J., Pedra J.H., Kotsyfakis M., Chmelař J. (2015): Modulation of host immunity by tick saliva. J Proteomics 128: 58-68.

Langhansová H., Bopp T., Schmitt E., Kopecký J. (2015): Tick saliva increases production of three chemokines including monocyte chemoattractant protein-1, a histamine-releasing cytokine. Parasite Immunol 37: 92-96.

Lieskovská J., Páleníková J., Langhansová H., Chagas A.C., Calvo E., Kotsyfakis M., Kopecký J. (2015): Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes. Parasite Vector 8: DOI: 10.1186/s13071-015-0887-1.

Lieskovská J., Páleníková J., Širmarová J., Elsterová J., Kotsyfakis M., Chagas A.C., Calvo E., Růžek D., Kopecký J. (2015): Tick salivary cystatin sialostatin L2 suppresses IFN responses in mouse dendritic cells. Parasite Immunol 37: 70-78.

Páleníková J., Lieskovská J., Langhansová H., Kotsyfakis M., Chmelař J., Kopecký J. (2015): Ixodes ricinus salivary serpin IRS-2 affects Th17 differentiation via inhibition of the interleukin-6/STAT-3 signaling pathway. Infect Immun 83: 1949-1956.

Palus M., Formanová P., Salát J., Žampachová E., Elsterová J., Růžek D. (2015): Analysis of serum levels of cytokines chemokines, growth factors, and monoamine neurotransmitters in patients with tick-borne encephalitis: Identification of novel inflammatory markers with implications for pathogenesis. J Med Virol 87: 885-892.

Procházka A., Dammer J., Weyda F., Sopko V., Beneš J., Zeman J., Jandejsek I. (2015): Biological object recognition in µ-radiography images. J Inst 10: C03023.

Strnad M., Elsterová J., Schrenková J., Vancová M., Rego R.O., Grubhoffer L., Nebesářová J. (2015): Correlative cryo-fluorescence and cryo-scanning electron microscopy as a straightforward tool to study host-pathogen interactions. Sci Rep doi: 10.1038/srep18029.

Weisheit S., Villar M., Tykalová H., Popara M., Loecherbach J., Watson M., Růžek D., Grubhoffer L., de la Fuente J., Fazakerley J.K., Bell-Sakyi L. (2015): Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis. Parasit Vectors, doi: 10.1186/s13071-015-1210-x.

Weyda F., Pflegerová J., Stašková T., Tomčala A., Prenerová E., Zemek R., Volter L., Kodrík D. (2015): Ultrastructural and biochemical comparison of summer active and summer diapausing pupae of the horse chestnut leaf miner, Cameraria ohridella (Lepidoptera: Gracillariidae). Eur J Entomol 112: 197-203.